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diagnosis algorithm approach calculation management mds myelodysplasia myelodysplastic pancytopenia production syndromes
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... malignancies • Infection ... • Toxins • Aplastic ... Nutritional deficiency ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
, MCV, MCH, MCHC ... • Aplastic Anemia ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... marrow failure: Aplastic ... #hematology #anemia ... #differential #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... ) - Differential ... Inflammation, Chronic Infection ... #MCV #Classification ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... index < 2 • EPO ... #Anemia #oncology ... #hematology #diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... Megaloblastic anemia-rare ... - Copper deficiency-rare ... white blood cell aplasia ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
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