51 results
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... (e.g. cancer, infection ... , G6PD deficiency ... #differential #
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Interpretation Iron deficiency ... , ↓ Ferritin Anemia ... Ferritin Iron deficiency ... Interpretation #deficiency ... #diagnosis #differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... 80 fL) • Iron Deficiency ... Inflammation, Chronic Infection ... #MCV #Classification ... #Differential #
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
secondary to iron deficiency ... as well as anemia ... To you help differentiate ... Diagnosis #Iron #Deficiency ... #Transferrin #Saturation
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Reactive: • Anemia ... blood loss (Fe deficiency ... ) • Infection/ ... Sepsis • Non-infectious
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... inflammation) • Iron deficiency ... Macroangiopathic, Infections ... , B12 deficiency ... MCV #Algorithm #Differential
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... #Classification ... #Approach #Differential
Causes of Vitamin B12 Deficiency - Cobalamin
Decreased Intake
Pancreas: Insufficiency
Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
of Vitamin B12 Deficiency ... Stomach: Pernicious anemia ... gastrectomy, H. pylori infection ... #Vitamin #B12 #Deficiency ... #Cobalamin #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential ... DAT (-) → G6PD Deficiency ... Fevers, DAT (-) → Infection ... #Differential #
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... malignancies • Infection ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional deficiency ... #Neutropenia #Differential