9 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... in pregnancy - Cholestatic ... Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Hepatocellular ... #Elevated #Abnormal ... #hepatology #LiverFunctionTests
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury Hepatocellular ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
(LFTs) Elevation ... ≥5: Hepatocellular ... #FunctionTest #LFTs ... #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Liver Injury Differential ... #Differential #Diagnosis ... #hepatology #algorithm ... #Transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... specificity to elevated ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Others • Cholestatic ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Intrahepatic Cholestasis ... necrosis HELLP Syndrome ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp