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diagnosis differential algorithm oncology sicklecell foam foamed pediatrics sicklecellanemia sicklecelldisease sicklecells causes hemolysis management microscopy rbc smear workup atlas bodies
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... anemia Sickled ... red cells: Sickle ... Smear #Analysis #hematology ... interpretation #clinical
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
syndrome (ST-HUS ... anemia" • HELLP ... syndrome • Catastrophic ... differential #diagnosis #hematology ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... uremic syndrome ... Hemoglobinopathies (e.g. sickle ... differential #diagnosis #hematology ... #anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... - Sickle cell anemia ... uremic syndrome ... #differential #hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Asplenism, Severe hemolytic ... anemia • Heinz ... , Hemolytic anemia ... , Thalassemia, Sickle ... Bodies #diagnosis #hematology
Treatments for Sickle Cell disease #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... #sicklecells #sickle ... #hematology #anemia ... #clinical #pediatrics
Cures for Sickle Cell disease #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Cures for Sickle ... #sicklecells #sickle ... #hematology #anemia ... #clinical #pediatrics
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Abnormal RBCs - Sickle ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Microangiopathic hemolytic ... defects (e.g. sickle ... Production #Index #hematology
Complications of Sickle Cell Disease slide 1/3 #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM
Complications of Sickle ... #sicklecells #sickle ... #hematology #anemia ... #clinical #pediatrics
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