16 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... folate/combined deficiencies ... #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... • Leukemia • Lymphoma ... Deficiencies: ... #Diagnosis #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... Volume (<80 fL) • Iron ... #MCV #Classification ... #Causes #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... MCH, MCHC, Serum Iron ... #Classification ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Acquired Aplastic Anemia ... #Hematology
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
Micronutrient Deficiencies ... ataxia), Korsakoff syndrome ... Trace Minerals: • Iron ... Bypass #vitamin #nutrition ... #table #differential
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Acquired Aplastic Anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... for workup, including ... hemolysis, deficiency anemia ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
e.g. lupus, CLL, lymphoma ... Defects: Enzyme deficiencies ... #differential # ... diagnosis #hematology ... #anemia
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... renal failure/uremia ... : • Lymphoma ... Myelodisplastic syndrome ... #causes