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diagnosis differential management hematology cardiology algorithm classification elevation nutrition signs acidosis agammaglobulinemia alkaline alp approach ascorbicacid b12 bronchiectasis celiac centralretinalartery
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... -12, or folate deficiency ... • Hemolytic anemia ... End-stage renal disease
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
Iron Deficiency ... of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Deficiency #Anemia
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... improvement in symptoms ... #deficiency #CHF
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
MCH, MCHC, Serum Iron ... Deficiency • ... B12/Folate Deficiency ... Disease • Marrow ... Diagnosis #Algorithm #Causes
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... - Iron deficiency ... associated with any symptoms ... #LDH #Lactate ... differential #diagnosis #Laboratory
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Suspected Celiac Disease ... • Signs and symptoms ... • Iron-deficiency ... anemia unresponsive ... without discernable cause
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... presentations and disease ... - assess other laboratory ... muscle use • Decreased ... 30mmHg) - Severe anemia
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... antibodies) -> Complete deficiency ... immunity Signs/Symptoms ... Agammaglobulinemia #XLinked #pathophysiology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... result in severe anemia ... immune hemolytic anemia ... elevation Serum lactate
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
, leading to a decrease ... central cobalt ion ... with vitamin B12 deficiency ... of pernicious anemia ... #Pathophysiology
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