16 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... RBC turnover • Iron ... • Hemolytic anemia ... End-stage renal disease ... Diagnosis #DM2 #Differential
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential ... Check the iron saturation ... of elevated ferritin ... Sideroblastic anemia ... extreme ferritin elevation
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Volume (<80 fL) • Iron ... #MCV #Classification ... #Differential #
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... MCH, MCHC, Serum Iron ... Disease • Marrow ... #Classification ... Diagnosis #Algorithm #Causes
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... Pressure - Differential ... hypovolemia - Severe iron ... Chronic pulmonary diseases ... Sympathetic overdrive • Elevated
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... deficiency - Iron ... Idiosyncratic LDH Elevation ... #differential # ... diagnosis #Laboratory
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Iron-deficiency ... anemia unresponsive ... treatment • Elevated ... without discernable cause ... microscopic colitis Differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... result in severe anemia ... Mild-to-moderate elevation ... WBC count and differential
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... conditions) • Severe iron ... deficiency anemia ... overdrive • Elevated ... coronary heart disease
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
presentations and disease ... Causes of elevated ... - assess other laboratory ... 30mmHg) - Severe anemia ... #typea #typeb #classification