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Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Chronic #Disease ... #Laboratory #Testing
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
↓ Transferrin Saturation ... , ↓ Ferritin Anemia ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... differential #hematology #laboratory
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Deficiency Anemia ... patients with anemia ... • Additional laboratory ... Test for celiac disease ... Gastrointestinal #Evaluation #workup
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
determine if their anemia ... is secondary to iron ... of chronic disease ... benefit from IV iron ... #Transferrin #Saturation
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Algorithm - Iron ... deficiency anemia ... chronic kidney disease ... #differential #workup
Causes of Hyperferritinemia - Differential Diagnosis Ferritin > 1000 Ferritin is the storage form of iron. Increased hepcidin
storage form of iron ... absorption of iron ... Iron overload - ... Check the iron saturation ... Sideroblastic anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (<80 fL) • Iron ... Poisoning • Anemia ... Marrow Failure • Anemia ... Diagnosis #Algorithm #Causes
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Gastrointestinal Causes ... of Iron Deficiency ... Anemia • Mass ... sprue, Whipple's disease ... ulcers, Crohn's disease
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Index < 2: • Anemia ... deficiencies: Iron ... Chronic kidney disease
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