15 results
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Chronic #Disease ... #Laboratory #Testing
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
↓ Transferrin Saturation ... , ↓ Ferritin Anemia ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... differential #hematology #laboratory
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Deficiency Anemia ... patients with anemia ... • Additional laboratory ... Test for celiac disease ... workup #diagnosis #gastroenterology
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
determine if their anemia ... is secondary to iron ... of chronic disease ... benefit from IV iron ... #Transferrin #Saturation
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
RBC turnover • Iron ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease ... HbA1c #HgbA1c #Laboratory
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... Index < 2: • Anemia ... deficiencies: Iron ... Chronic kidney disease
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Suspected Celiac Disease ... Algorithm Celiac disease ... • Iron-deficiency ... anemia unresponsive ... Diagnosis #Algorithm #gastroenterology
Anemia of Chronic Disease - Pathophysiology
One theory to explain why "anemia of chronic disease" exists:
The inflammatory
Anemia of Chronic ... Disease - Pathophysiology ... often require iron ... ability to lock up iron ... #pathophysiology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
causes of liver disease ... other causes of iron ... ; HIC, hepatic iron ... saturation. ... management #hepatology #gastroenterology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... - Pernicious anemia ... deficiency - Iron ... • Legionnaires disease ... differential #diagnosis #Laboratory