16 results
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing

SUMMARY:
 - RDW, FEP, serum iron,
Iron Deficiency ... of Chronic Disease ... - Laboratory Testing ... , saturation-worthless ... #Deficiency #Anemia
Iron Panel Interpretation

Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation,  ↓
Iron deficiency ... , ↓ Ferritin Anemia ... deficiency + Chronic ... Interpretation #deficiency ... differential #hematology #laboratory
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Deficiency Anemia ... • Additional laboratory ... Test for celiac disease ... #Deficiency #Anemia ... workup #diagnosis #gastroenterology
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
is secondary to iron ... deficiency as well ... disease. ... #Deficiency #Anemia ... #Transferrin #Saturation
Causes of Iron Deficiency
 • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : IBD, Chronic disease ... #Deficiency #Causes ... differential #diagnosis #anemia ... #nutrition
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... Edema, Celiac disease ... IBD, cancer) #Iron ... diagnosis #causes #nutrition
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
RBC turnover • Iron ... -12, or folate deficiency ... • Asplenia Laboratory ... • Hemolytic anemia ... End-stage renal disease
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Chronic kidney disease ... , G6PD deficiency
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
Suspected Celiac Disease ... Algorithm Celiac disease ... • Iron-deficiency ... anemia unresponsive ... Diagnosis #Algorithm #gastroenterology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... , deficiency of ... - Pernicious anemia ... - Iron deficiency ... differential #diagnosis #Laboratory