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diagnosis hepatology rheumatology workup anemia arthritis associations autoantibodies calculation causes cellulitis cholangitis clinical coagulation comparison dic differential disease diseases disseminated
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary Biliary ... Cirrhosis vs Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... PBC Signs and ... #Cirrhosis #PBC
Erythropoiesis (RBC Production and Maturation) Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis (RBC ... Production and ... Erythropoiesis #RBC ... #Production #Maturation ... #hematology #pathophysiology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Reticulocyte Production ... transform into a RBC ... deficiencies: Iron ... anemia, Intrinsic RBC ... #Index #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... diagnosis #table #rheumatology ... #antibodies
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... HIT: Heparin-PF4 antibodies ... hydration • RBC ... treatment #management #hematology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
skin infection Cirrhosis ... Hippocrates in 5 BC ... sepsis: chronic liver ... can sequester iron ... rash #cellulitis #dermatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
double-stranded DNA antibodies ... Complete blood count (CBC ... profile, including liver ... ferritin level, and iron ... saturation of serum
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