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differential algorithm hepatology causes anemia management primary syndrome biliary workup dermatology lfts rbc rheumatology treatment atlas cbc cellulitis cholangitis clinical
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Primary Biliary Cirrhosis ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
↓ Transferrin Saturation ... nl Transferrin Saturation ... ↓ Transferrin Saturation ... Interpretation #deficiency #diagnosis ... #differential #hematology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary Cirrhosis ... relative with PBC ... Cholestasis #PBC ... Primary #Biliary #Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... cholestasis → Cirrhosis ... Diagnosis: • ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... #PBC #Primary ... #Biliary #Cirrhosis ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... Non malignant hematologic ... malignancy • Iron ... #Differential #Diagnosis
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... Tests: • MCV/RBC ... - RBC ↓ in proportion ... #ferritin #Fe #diagnosis ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #differential #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... MCH, MCHC, Serum Iron ... Reticulocytes • Iron ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Transaminitis #Algorithm #diagnosis ... #hepatology #LiverFunctionTests
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