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differential anemia management morphology rbc workup algorithm aplastic arthritis bandemia bloodcell calculation causes cbc coagulation dic disease disseminated fungal hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
x (Hct / 45) / Maturation ... Factor The maturation ... deficiencies: Iron ... #hematology #anemia ... #differential #diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
) Morphology Atlas ... • Microcytic - Iron-deficiency ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Thalassemia, Iron ... elliptocytosis, Severe iron ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... erythropoietin (EPO), iron ... substrate (e.g. iron ... OR reticulocyte index ... #Workup #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Differential Diagnosis ... likelihood of negative clinical ... #CBC #hematology ... #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... hydration • RBC ... #Coagulation #diagnosis ... treatment #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... • ↓ WBC • ↓ ... • Reticulocyte index ... Anemia #oncology #hematology ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... ferritin level, and iron ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... of orthodeoxia CLINICAL ... • Stigmata of cirrhosis ... digital clubbing DIAGNOSIS ... #diagnosis #hepatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... neutropenia, and iron ... relies on a high index ... , neutropenia, cirrhosis ... Aspergillosis Pathophysiology
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