11 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
Workup Algorithm by CBC ... and LFT Pattern ... Workup #Algorithm #Patterns ... #LFTs #Diagnosis ... #Hepatology #Differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... Initial Workup: CBC ... reticulocyte count, LFTs ... LDH, ESR, CRP, iron ... #hematology #workup
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #LFTs #transaminitis ... #differential # ... diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... • Others #LFTs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... Diagnosis: • ... bile ducts Differential ... #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Factor The maturation ... deficiencies: Iron ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... hepatitis: < 1 • Cirrhosis ... liver #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... body mass index; FBC ... #LFTs #Abnormal ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
function tests (LFTs ... ferritin level, and iron ... saturation of serum ... (to support a diagnosis ... laboratory #workup #diagnosis