10 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
Approach to Jaundice Workup ... Algorithm by CBC ... and LFT Pattern ... #LFTs #Diagnosis ... #Hepatology #Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... bile ducts Differential ... #PBC #cholangitis ... #diagnosis #workup ... #hepatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Factor The maturation ... deficiencies: Iron ... #hematology #anemia ... #differential # ... diagnosis #calculation
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Diagnosis Algorithm ... /uL Initial Workup ... : CBC with diff, ... LDH, ESR, CRP, iron ... #hematology #workup
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Hepatocellular Pattern ... Congenital, Others, Cirrhosis ... #hepatology #LiverFunctionTests
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... • CHOLANGITIS ... of UDCA for all patietns ... #diagnosis #management ... #summary #Hepatology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... erythropoietin (EPO), iron ... substrate (e.g. iron ... OR reticulocyte index ... #Workup #Hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework
LOW RETIC INDEX - ↓ PRODUCTION
 • Vitamin
- Differential ... Diagnosis Framework ... LOW RETIC INDEX ... Alcohol related, Iron ... Diagnosis #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... BMI, body mass index ... ; FBC, full blood ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Liver disease: Cirrhosis ... autoimmune hepatitis, PBC ... gastric tumors • Hematology ... #diagnosis #hematology