16 results
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Diagnosis Algorithm ... oral intake Renal ... tubular acidosis ... • Gitelman's ... #Algorithm #Causes
Renal Tubular Acidosis - Diagnosis Algorithm
 • Hyperkalemic Type 4 RTA
 • Hypokalemic Type 1 RTA
Renal Tubular Acidosis ... - Diagnosis Algorithm ... Type 4 RTA • Hypokalemic ... #Diagnosis #Algorithm ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... (renal potassium ... tubular acidosis ... #Syndrome #diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... Algorithm Defining ... • Renal tubular ... Bartter's syndrome, Gitelman's ... #nephrology #potassium
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... #Diagnosis #Differential
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... in the distal tubule ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology ... #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Extra-renal Losses ... loss (Diarrhea) Renal ... Bartter syndrome, Gitelman
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Renal Tubular Acidosis ... - Differential Diagnosis ... Algorithm Decreased ... Urine pH > 6.0 - Hypokalemic ... #Algorithm #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
- Differential Diagnosis ... Algorithm GI Losses ... Chloridorrhea Renal ... Losses - Impaired tubular ... Hypomagnesemia • Barrter's/Gitelman's
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... suggests extra-renal ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology