9 results
Carbon Monoxide Poisoning
Clinical 
 • Headache 
 • Nausea / vomiting 
 • Loss of consciousness
Hypoxia, chest pain ... Management ... Severe metabolic acidosis ... Monoxide #Poisoning #Toxicology ... #Diagnosis
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
- Abdominal pain ... , nausea, vomiting ... and metabolic acidosis ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... patient’s complete medical ... laboratory or diagnostic ... - Compartment syndrome ... Severe anemia - Carbon
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
(PRIS) Diagnosis ... • Metabolic acidosis ... #PRIS #Diagnosis ... #Management #Pharmacology ... #Toxicity #Toxicology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion syndrome ... (PRIS) - acidosis ... No pharmacologic ... #CriticalCare #diagnosis ... #management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Renal Excretion Carbonic ... • Diagnosis of ... irrigation • Management ... Kidney stones caused ... Diuresis #Nephrology #Pharmacology
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
adhesives, stains, paint ... gasoline additive Pharmacology ... , but does NOT cause ... osmolal gap #Diagnosis ... #Management #Toxicology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... renal tubular acidosis ... lubricants • Pharmacologic ... #Management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... Pleuritic chest pain ... pneumonitis Diagnosis ... Exclude other causes ... #management #Toxicology