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management differential rheumatology oncology hemophagocytic lymphohistiocytosis pancytopenia syndrome testing activation arthritis behcet cancer chronic classification deficiency gastroenterology hemochromatosis hemolytic hepatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Algorithm Consumption ... Acquired Aplastic Anemia ... Metastatic Disease ... #Algorithm #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
: Ferritin, iron ... Structural: Celiac disease ... diet, Alcoholism, Tea-toast ... #Algorithm #ferritin ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : HLH signs and ... Low or absent NK cell ... activity • Ferritin ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
dysfunction, ↑ Ferritin ... • Autoimmune diseases ... Unknown cause Treatment ... Nicolas Taar ... #management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... Consider sickle cell ... #Algorithm #workup ... #hematology #testing
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... causes of liver disease ... concentration; SF, serum ferritin
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
with leukopenia, anemia ... dehydrogenase • ↑ Ferritin ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
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