28 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... telomeropathy Cancer ... Antibody-mediated hemolysis ... #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... PD deficiency, Pulmonary ... uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
extravascular) hemolysis ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... diet, Alcoholism, Tea-toast ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... blood loss, Acute hemolysis ... , deficiency anemia ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... of anemia include ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... Legionnaires disease • Pulmonary ... • Tumor lysis syndrome ... associated with any symptoms ... #differential #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... #diagnosis #dermatology ... #oncology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- CHF - Pulmonary ... -DPG -> - hemolysis ... - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
cancer for which ... No evidence of anemia ... constitutional symptoms ... insufficiency, Anemia ... #diagnosis #oncology