73 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... Hemolysis #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology ... GrepMed Recommended Text
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... K), H. pylori test ... thyroid function test ... changes), high MCV anemia ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Systemic lupus erythematosus ... Differential #Diagnosis #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Systemic #Lupus #Erythematosus
Mucous Membrane Disorder - Differential Diagnosis Algorithm
Erosions/Ulcers/Blisters
 - Primary Dermatologic Diseases
     •
Stevens-Johnson Syndrome ... Systemic lupus erythematosus ... • Behcet's syndrome ... MucousMembranes #dermatology ... Diagnosis #Algorithm #causes
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... HLH syndrome 5. ... Acquired Aplastic Anemia ... Metastatic Disease ... Diagnosis #Algorithm #Hematology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
of renal disease ... • Renovascular disease ... • Cushing’s syndrome ... Mineralocorticoid excess syndromes ... #Screening #Workup
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... Alcohol use, Liver disease ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... lymphoma • Evans' syndrome ... Shrinking lung syndrome ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia