13 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure (ACLF) Clinical ... those with CLD (± cirrhosis ... Drug-Induced Liver Injury ... #Hepatology #gastroenterology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ascites removed • Acute ... kidney injury ( ... Indications #Management #Cirrhosis ... #treatment #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... Drug-induced liver injury ... Differential #Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... Patterns #Liver #Injury ... #hepatology #LFTs
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Criteria HRS-AKI (Acute ... in 3 months • Cirrhosis ... structural kidney injury ... HRS-NAKI (Non-Acute ... HRSAKI #HRSNAKI #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... Clues to non-cirrhotic ... /acute hepatitis ... Primary biliary cirrhosis ... Diagnosis #causes #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... hepatitis: < 1 • Cirrhosis ... : > 1 • Acute ... muscle injury: > ... #differential #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Family history of cirrhosis ... or fibrosis • Cirrhosis ... with severe liver injury ... > 3 mg/dL) or acute ... Indications #management #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis Clinical ... Highly variable clinical ... subclinical disease to acute ... pattern of liver injury ... Diagnosis #Management #Hepatology