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diagnosis management latenttb rheumatology syndrome tb treatment tuberculosis agglutinin aids anemia apml betadglucan classification cmv cold cytomegalovirus differentiation disease erythematosus
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... Tuberculin skin test ... staining, NAA (PCR
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Pulmonary fibrotic ... • HIV: 2/3 pulmonary ... destruction (including pulmonary ... Tuberculin skin test ... staining, NAA (PCR
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH ... Internal (RBC) - Infections ... Laboratory Tests ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
younger pts) Differential ... Hemoglobinuria (PCH ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
CMV infection: virus ... : Quantitative PCR ... pp65 antigenemia test ... Pancreatitis • Pulmonary ... AIDS #diagnosis #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... diagnosis #management #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... Leishmaniasis Differential ... • Persistently active ... Inflammatory #Syndrome #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... progressing GN • New pulmonary ... to exclude are infections ... retinopathy Lab Tests ... #diagnosis #rheumatology
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Other +s: PCP, Histo ... surfaces, Albumin, Infections ... the use of this test ... in BAL does not differentiate ... concurrent admin mold-active
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