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liver differential injury management causes lfts transaminitis aclf ascites autoimmune chemistry chronic cirrhosis dili druginduced gastroenterology hepatocellular interpretation rvalue saag
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... dechallenge • Acute ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Infections Alcohol-Associated ... Hepatitis (AAH) ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #Differential #Diagnosis ... #algorithm #hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... only increase short-term ... survival in severe AH ... #Algorithm #treatment ... #hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... : - Acute kidney ... failure or shock ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
evidence of liver failure ... • Infections: Hepatitis ... Drugs (MDMA), Alcohol ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... #algorithm #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... , AIH diagnosis ... #AIH #Diagnosis ... #Management #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Cirrhosis - Alcoholic ... hepatitis ... fibrosis - Acute ... Ascites #Causes #diagnosis ... #differential #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... Liver Failure ( ... ALT Ratios: • Alcoholic ... liver #chemistry #diagnosis ... #differential #Hepatology
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