12 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... to GBM disruption ... Proteinuria often ... Massive proteinuria ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... proliferative • Anti-GBM ... #Nephrology #Differential ... #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
disease (hematuria, proteinuria ... Basement Membrane (GBM ... staining on IF • No EM ... #Differential #Diagnosis ... #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
RBC casts, +/- proteinuria ... immune deposits on EM ... anti-phospholipid syndrome ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... hemolytic-uremic syndrome ... heart disease, ear ... #nephrotic #syndrome ... #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... Exam This 28 year ... One and a Half Syndrome ... the hospital, diagnosed ... ophthalmology #neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
cases/100,000 per year ... - HIV, CMV, EBV ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Electron Microscopy (EM ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... glomerular #diseases #nephrology ... comparison #table #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... • Hematuria, proteinuria ... glomerulonephritis) • Anti-GBM ... • Cogan Syndrome ... well as inner ear