19 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... and Nephrotic Syndromes ... to GBM disruption ... diabetes)) #Glomerular ... Proteinuria #Nephrology #Diagnosis
Common Causes of the Different Categories of Dizziness #Diagnosis #PrimaryCare #EM #IM #Differential #Dizziness #Vertigo #Disequilibrium
of Dizziness #Diagnosis ... #PrimaryCare #EM ... Lightheadedness #Table ... #NEJM
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... = glomerular basement ... hemolytic-uremic syndrome ... heart disease, ear ... #nephrotic #syndrome
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... Differential Diagnosis ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... #differential #diagnosis
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... pathology #comparison #table ... #diagnosis #microscopy
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Fanconi's syndrome ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Differential #Diagnosis
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
patients with Stable ... acute coronary syndrome ... #ISCHEMIA #Stable ... Angina #ChestPain #Diagnosis ... Algorithm #Cardiology #EBM
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Body Myositis (IBM ... MSAs #clinical #diagnosis ... #rheumatology #table
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... immune deposits on EM ... anti-phospholipid syndrome ... MPGN #nephrology #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... Celiac disease Anti-GBM ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology