52 results
Ophthalmoplegia secondary to Orbital Apex Syndrome

A 61-year-old man presented with retro-orbital pain, near-complete ophthalmoplegia, loss of
to Orbital Apex Syndrome ... A 61-year-old ... retro-orbital pain, near-complete ... Orbital #Apex #Syndrome ... #PhysicalExam #NEJM
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Features: alveolitis, ear ... myelodysplastic syndrome ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... Hypereosinophilic #Syndrome ... #HES #Hematology ... eosinophils #diagnosis #management
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Myopathy #Comparison #Managment ... #algorithm #Rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Diagnosis and Management ... acute leukemia Management ... Myelodysplastic #Syndrome ... #treatment #hematology
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... disease flares - 2-year ... David #Susac #Syndrome ... Triad #Diagnosis #Management ... #Rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #Diagnosis #Management ... #treatment #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
1) 2+ flares/year ... gout #diagnosis #management ... treatment #ULT #rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome ... Sarcoidosis #Diagnosis #Management