18 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
- Decreased tear ... Decreased saliva production ... Decreased mucous production ... Decreased sebum production ... Sjogrens #Syndrome #Pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
mucins with reduced tear ... production -> Corneal ... #Xeropthalmia #pathophysiology ... #ophthalmology
Acute Otitis Externa (Swimmer’s Ear): Pathogenesis and clinical findings
Pathogens = Pseudomonas aeruginosa (most common opportunistic), Staphylococcus,
Externa (Swimmer’s Ear ... canal -> Decreased production ... #SwimmersEar #pathophysiology
Hyperopia: Pathogenesis and clinical findings
 • Axial length of eye -> Short axial length of the
distant vision • Near ... retina -> Blurry near ... #Hyperopia #pathophysiology ... #ophthalmology
Aqueous Humor Production and Drainage
 • Provides nutrition, removes wastes, and transports neurotransmitters to the avascular
Aqueous Humor Production ... pathways located near ... #AqueousHumor #Production ... Drainage #flow #Pathophysiology ... #ophthalmology
Major Physiological Effects of Angiotensin II

Altered Peripheral Resistance
I. Direct vasoconstriction
II. Enhancement of peripheral noradrenergic
neurotransmission:
  A.
expression of proto-oncogenes ... Increased production ... AngiotensinII #Pathophysiology
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
RPE -> Loss of photo ... MacularDegeneration #pathophysiology ... #ophthalmology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... blood cells + production ... Nicolas Taar
Conjunctivochalasis is defined as a redundant, nonedematous conjunctiva that causes a wide variety of symptoms ranging
of an unstable tear ... disruption of tear ... conjunctivochalasis #ophthalmology ... dry #clinical #photo
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis infections/year ... tuberculosis (LTBI) Pathophysiology ... Night sweats • Productive