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diagnosis management treatment differential disease hematology comparison cppd erythematosus gout hemophagocytic hlh lupus lymphohistiocytosis neurology signs sle systemic vasculitis abnormal
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... Features: alveolitis, ear ... myelodysplastic syndrome ... and/or 2) Inflammatory ... Autoinflammatory #Somatic #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Treatment: • Inflammatory ... CNS #neurology #rheumatology
Ear Pain (Otalgia) - Differential Diagnosis Framework Primary Otalgia - Pain that originates from the ear
- Ramsay Hunt syndrome ... • Melanoma Inflammatory ... Nerve V: • TMJ syndrome ... Infection • Inflammatory ... vision or black spots
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Distinguishing between Inflammatory ... joint disease Inflammatory ... joints tend to bear ... > Stiffness is short-lived ... JointPain #Diagnosis #pathophysiology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic inflammatory ... often a nonerosive inflammatory ... anterior chest wall, parts ... findings: Nonspecific inflammatory ... #Rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... Disease (25-75%): Inflammatory ... tests in Behcet syndrome ... Giant retinal tears ... signs #symptoms #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... cases/100,000 per year ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... Miller Fisher Syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... production of pro-inflammatory ... Nicolas Taar ... treatment #summary #rheumatology
Immune Reconstitution Inflammatory Syndrome (IRIS) - Pathophysiology Risk factors: - Low CD4 count - Disseminated OI -
Syndrome (IRIS) ... - Pathophysiology ... OI (in CM) - Short ... #Syndrome #IRIS ... #Pathophysiology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of 37°C to the near-freezing ... (COVID-19) • Inflammatory ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
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