25 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... erythematosus (SLE) Signs ... - Decreased tear ... #Pathophysiology ... #Diagnosis #Signs
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
mucins with reduced tear ... conjunctiva) • Bitot's spots ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis #signs
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... inhibitors • Incr Pro-inflammatory ... • Rizutti's Sign ... #Keratoconus #pathophysiology
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... bariatric surgery, Inflammatory ... Chronic diarrhoea, Short ... bowel syndrome, ... , Malnutrition Signs
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
- Ramsay Hunt syndrome ... • Melanoma Inflammatory ... Nerve V: • TMJ syndrome ... Infection • Inflammatory ... vision or black spots
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Distinguishing between Inflammatory ... joint disease Inflammatory ... joints tend to bear ... > Stiffness is short-lived ... JointPain #Diagnosis #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
, rotator cuff tear ... inflammation as post-inflammatory ... stop, but post-inflammatory ... FrozenShoulder #pathophysiology ... diagnosis #symptoms #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... cases/100,000 per year ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... Miller Fisher Syndrome