18 results
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action ... #Diuretics #Mechanism ... #pharmacology #pathophysiology ... #nephrology
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
Mechanisms of thiazide ... #pharmacology #pathophysiology ... adverseeffects #nephrology
Mechanisms of Cocaine induced AKI

 • Rhabdomyolysis
 • Vasculitis
 • Infarction
 • Acute interstitial nephritis
 •
Mechanisms of Cocaine ... #induced #AKI #nephrology ... #pathophysiology ... #table
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis:
https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext

#Pathophysiology #Mechanism #Nephrology
-4/fulltext #Pathophysiology ... #Mechanism #Nephrology
Regulation of GFR
Physiologically, GFR is auto-regulated very precisely with changes in the mean arterial pressure (MAP)
Mechanisms of auto-regulation ... - Myogenic mechanisms ... Neuro-hormonal feedback #Pathophysiology ... #Nephrology #GFR
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... cardiorenal #syndrome #Mechanisms ... #pathophysiology ... #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Subclass, Drug, Mechanism ... Pharmacology #summary #table ... #nephrology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... transfusion • Pathophysiology ... diagnosis #comparison #table
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
radiocapitellar line • Mechanism ... • If stable ... Ulnar #Radiology #XRay
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
majority of cases) -> Mechanism ... ultrasound and/or x-ray ... osteophytes seen on x-ray ... Signs #Symptoms #Pathophysiology