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Inhibitors of Platelet Aggregation

#Antiplatelet #Inhibitors #Pharmacolgy #Pathophysiology #MechanismOfAction
Inhibitors of Platelet ... #Antiplatelet #Inhibitors ... Pathophysiology #MechanismOfAction
Mechanism of Action of Platelet Aggregation Inhibitors
- COX Inhibitors
- ADP Inhibitors
- GP IIb/IIIa Receptor Blockers

#Antiplatelet #Pharmacolgy
Platelet Aggregation Inhibitors ... - COX Inhibitors ... - ADP Inhibitors ... #Pharmacolgy #MechanismOfAction
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
Table Aspirin - Inhibits ... combination with P2Y12 inhibitor ... in a-fib P2Y12 Inhibitors ... ticagrelor) - Inhibits ... , abciximab) - Inhibits
HIV HAART Medications - Classification by Names and Mechanism - Updated 01/2021
 - NRTIs
 - NNRTIs
NNRTIs - Protease Inhibitors ... - Integrase Inhibitors ... Antagonist - Fusion Inhibitor ... - Attachment Inhibitor
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... Renin release inhibition ... Angiotensin-converting enzyme (ACE) inhibitors ... of aldosterone inhibition ... • Calcineurin Inhibitors
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Between P2Y12 Inhibitors ... Oral P2Y12 inhibitors ... Switching P2Y12 inhibitors ... between P2Y12 inhibitors ... and Oral P2Y12 Inhibitors
HIV Antiretroviral Medications Cheat Sheet

NRTIs
Integrase Inhibitors
NNRTIs
PIs
Fusion Inhibitors
CCR5 Antagonist
Post Attachment Inhibitor
Combination Pills
NRTI-Sparing
Resistance Mutations Summary - https://hivdb.stanford.edu/ 

By
NRTIs Integrase Inhibitors ... NNRTIs PIs Fusion Inhibitors ... Post Attachment Inhibitor
HIV Antiretroviral Pharmacokinetic Boosters - Ritonavir & Cobicistat 

Ritonavir & Cobicistat are 2 pharmacokinetic boosters used
are both CYP3A4 INHIBITORS ... actually a protease inhibitor ... and a 3A4 inhibitor ... is just a 3A4 inhibitor ... because of the CYP inhibition
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Direct or indirect inhibitory ... direct thrombin inhibitors ... Inhibitors: Non ... specific inhibitor ... antibodies), Specific inhibitors
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Direct Xa inhibitors ... Specific inhibitors ... Nonspecific inhibitors ... Specific inhibitors ... Inhibitors