22 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... of Pregnancy (AFLP ... ) Three syndromes ... tests, Low Platelets ... #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Three syndromes ... Hemolysis, Elevated Liver ... tests, Low Platelets ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... develops (DIC, ascites ... infiltration) Differential ... iMedEducation #AFLP ... Pregnancy #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... Algorithm #diagnosis #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
necrosis HELLP Syndrome ... of Pregnancy (AFLP ... #hepatology #obstetrics ... hepatitis #comparison #differential ... diagnosis #icp #HELLP #AFLP
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Pregnancy) - Low ... Myelodysplastic Syndromes ... Function Tests ... Algorithm #Causes #Hematology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... of pregnancy ... Causes #diagnosis #differential ... #hepatology #SAAG
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... melanoma, myeloma • Pregnancy ... extrahepatic source - Tests ... • Gilbert's syndrome
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... of portal HTN: ascites ... and hepatorenal syndrome ... portal HTN: • Ascites ... of pregnancy
Spontaneous Bacterial Peritonitis (SBP) - Diagnosis and Management
Ascites PMN > 250/mm3
? Nosocomial or hospital acquired. Recent
Ascites PMN > ... cefotaxime) SBP: Medical ... prophylaxis - Best ... dysfunction or liver ... #hepatology