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diagnosis management oncology syndrome adult cardiacarrest lifesupport cancer capillary circular clarksons comparison differential differentiation disease disorders emergencies eosinophil eosinophilia essential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... common • Imaging: CXR ... - pulmonary opacities ... unless severe APLS ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... incidentally during medical ... for secondary causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
Adult ACLS - Cardiac Arrest Algorithm - AHA 2020 CPR Quality: • Push hard (at least 2
Adult ACLS - Cardiac ... Arrest Algorithm ... intra-arterial Reversible Causes ... , Thrombosis, (pulmonary ... #AHA2020 #management
Adult Cardiac Arrest - ACLS Circular Algorithm - AHA 2020 CPR Quality: • Push hard (at least
Cardiac Arrest - ACLS ... Circular Algorithm ... intra-arterial Reversible Causes ... , Thrombosis, (pulmonary ... #AHA2020 #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... have fever - ACS ... organ damage • Treatment ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... , Median age 50 ... filling +++ (risk of pulmonary ... spacing of IVIg cures ... #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Exposure to heavy metal ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Treat underlying cause ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... transformation into MDS or AML ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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