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causes systemic sle dermatology algorithm ana antinuclear classification alopecia antibodies hairloss vasculitis anemia autoantibodies diffuse druginduced patterns table treatment activation
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... disease (MCTD), Drug-induced ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Lupus Classification Spontaneous Lupus - Cutaneous Lupus Erythematosus (CLE) - Systemic Lupus Erythematosus Drug-Induced Lupus - Drug-Induced
Erythematosus ( ... Erythematosus ... Drug-Induced Lupus ... #rheumatology # ... diagnosis #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Wiskott-Aldrich syndrome ... Diseases: • Systemic lupus ... erythematosus ... #Diagnosis #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus ... #skin #rashes #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... extremities Drug ... • Antihistone: Drug ... activation and/or medications ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Diagnosis and Lupus ... Mimickers: Drug-induced ... #Erythematosus ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... #Erythematosus ... #SLE #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Demyelinating Syndrome ... #Erythematosus ... CNS #neurology #rheumatology ... #management #treatment
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Diagnosis Algorithm ... Congenital Medications ... Destruction • Systemic Lupus ... Erythematosus ... #Causes #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus ( ... #differential # ... hematology
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