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causes hematology dermatology systemic generalized oncology pancytopenia workup chronic management mds myelodysplasia myelodysplastic naildisorders neutropenia primary syndromes thrombocytopenia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome ... #Diagnosis #Algorithm
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Presentation: • Fever • Fatigue ... - Antithyroid medications ... #hematology #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Hyperthyroidism • Diabetes ... Hematologic • Anemia ... #Fatigue #Differential ... #Diagnosis #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Drugs Nutritional ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Diagnosis #Algorithm
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Blood Glucose: • Diabetes ... Myelodisplastic syndrome ... #primary #secondary ... #Diagnosis #Algorithm
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Diagnosis Algorithm ... Drugs Nutritional ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Diagnosis #Algorithm
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Discoloration • Medications ... heart failure • Diabetes ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... Blood Glucose: • Diabetes ... Myelodisplastic syndrome ... #secondary #systemic ... #Diagnosis #Algorithm
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... Diagnosis Neonate ... Megaloblastic anemia-rare ... white blood cell aplasia ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... DDX: Rule Out Secondary ... • Aplastic Anemia ... blood count with differential ... #diagnosis #hematology
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