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hematology causes algorithm systemic lad chronic cll diffuse focal generalized hodgkins localized lymphocytic management pathophysiology pruritus acquired agglutinin allergy anemia
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
- Differential ... • Neoplastic (Leukemia ... , Lymphoma, Metastatic ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse Lymphadenopathy ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
- Differential ... Diagnosis Algorithm ... Tularemia • Secondary ... #Causes #Hematology ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
Diagnosis of Lymphadenopathy ... Kaposi sarcoma, leukemias ... , lymphomas, metastases ... venereum, primary and secondary ... arthritis, Sjögren syndrome
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 Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Disorders - Differential ... Diagnosis Algorithm ... (NHL) ~60% - lymphadenopathy ... Treated Like Acute Leukemias ... #Classification
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... Chronic inflammatory disorders ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... #hematology #secondary
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involved) • No leukemic ... translocation • Types: Classification ... disease: B symptoms, lymphadenopathy ... NonHodgkins #comparison #oncology ... #diagnosis #differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
: • Lymphoma ... • Leukemia • ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
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