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diagnosis hematology obstetrics pregnancy transaminitis hellp hepatitis injury table algorithm anemia atlas bleeding bruising causes chemistry coagulation deficiencies deficiency disease
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
HELLP Syndrome and Acute ... Pregnancy (AFLP) ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... diagnosis #table #comparison
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... Cirrhosis: > 1 • Acute ... #Hepatology #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Hepatopathy • Acute ... #Differential # ... Diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... headache, malaise) → Acute ... infiltration) Differential ... Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Vascular Causes of Acute ... Hepatocellular Acute ... Cholestatic Acute ... Cirrhosis: > 1 • Acute
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
and hemorrhage Acute ... Pregnancy (AFLP) ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... Post-partum • Acute ... catastrophes, Acute ... Summary #table #comparison ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Megaloblastic anemia, Liver ... - Thalassemia, Liver ... Malignant tumors, Acute ... key #diagnosis #differential ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, Acute ... : Alcohol use, Liver ... morphologic #mcv #differential ... diagnosis #causes #hematology
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