16 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Presentation: Subacute-Acute ... • Rare: DAH, acute ... initiation • Differential ... , Anaphylaxis, Acute ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... (Acute Myeloid ... (Acute Promyelocytic ... #Leukemia #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... • Rheumatoid Arthritis ... Fatigue • Acute ... Pancytopenia, WBC differential ... Algorithm #Causes #Hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint Pain ... History: Is the pain ... : • Acute or chronic ... #MSK #rheumatology ... approach #workup #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... the time course (acute ... MONOARTHRITIS • Acute ... asymmetric pattern Acute ... Joint #pain #Differential
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Fever/Chills/Joint pain ... Reactive Syndrome - Acute ... Effusions: - Hematologic ... diagnosis #msk #physicalexam
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm Acute ... • Myloid (AML ... Blood #Disorders #hematology ... #Markers #Differential
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... • Fracture • Arthritis ... Immobilization) • Acute ... #differential # ... extremity #msk #physicalexam
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... vomiting, abdominal pain ... headache, malaise) → Acute ... infiltration) Differential ... #obstetrics #obgyn
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... Chronicity: • Acute ... infections (bacterial), acute ... • Acute = Viral ... approach #workup #differential