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Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Urticarial/LCV) - Cryoglobulinemic ... - GPA Cutaneous ... : • Behcet Disease ... #skin #dermatology
Skin Ulcers of the Lower Legs / Feet - Differential Diagnosis Algorithm
Physical:
• Pressure
• Trauma
• Radiation
Vascular:
• Arterial
insufficiency • Vasculitis ... cell carcinoma • Melanoma ... #Feet #Ulcers #ulcerative ... #skinrash #dermatology ... Diagnosis #Algorithm #causes
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... #dermpath #dermatology ... lesions #diagnosis #clinical ... pathology #lesions #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Bullae/Blisters • Ulceration ... reticularis Differential ... #dermatology #rash
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... vasculitis Clinical ... involvement - Less ... with refractory disease ... #Vasculitis #Rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /HSP • Cryoglobulinemia ... - GPA - EGPA ... #Diagnosis #hematology ... #nonpalpable #dermatology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
insufficiency • Vasculitis ... carcinoma • Melanoma ... Thalessemia • Cryoglobulinemia ... #skinrash #dermatology ... Diagnosis #Algorithm #causes
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... arthralgia, arm/leg ... MPO > PR3 60/ GPA ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... more): Genital ulceration ... ) Differential Diagnosis ... Lymphoma Ocular melanoma ... Syndrome #diagnosis #management