12 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... , Arthritis, myalgia ... , SCLE-DIL (terbinafine ... constitutional symptoms
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
erythema nodosum (septal ... Oral aphthae : SLE ... : SLE, Reactive ... Syndrome #diagnosis #management ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... Joints (90%): Aseptic ... of hip (rare), Arthritis ... erythematosus #signs #symptoms
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
history of trauma, sepsis ... organ damage Clinical ... Subcutaneous dissecting hematoma ... causes #treatment #management ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... MAS, Visceral, DIC ... splenomegaly • Hepatic ... Disease #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... erythematosus [SLE ... brucellosis) • Sepsis ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... , APLA, PAC • Aseptic ... vein thrombosis Hematologic ... Induced Lupus: • Symptoms
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis ... shoulders Signs & Symptoms ... Ultrasound Diagnosis: CLINICAL ... #diagnosis #management ... #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... , Arthritis, myalgia ... , SCLE-DIL (terbinafine ... #rheumatology # ... diagnosis #treatment #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... +++ (Plt, Hb), Hepatic ... Autoimmune diseases: SLE ... Lymphohistiocytosis #diagnosis #management