23 results
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... - Acute CPPD ... polyarticular arthritis ... #Disease #Signs ... #Symptoms #Pathophysiology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... of Joint Disease ... disease must be ... trauma (e.g., meniscal ... #Pain #MSK #rheumatology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... diseases features ... Extra-articular signs ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
crystals from joints ... and/or x-ray - CPPD ... warm, swollen joint ... #Disease #Signs ... #Symptoms #Pathophysiology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Chondrodysplasia Neurologic ... #causes #symptoms ... #signs #diagnosis ... #msk
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... ) - MSK Radiology ... mass and NO prior signs ... (RA, CPPD) - Can ... diffuse chondral disease
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... years after • Arthritis ... - Large joints ... #diagnosis #signs ... #symptoms
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
(CPPD) Pathophysiology ... swelling in weird joints ... metacarpophalangeal joints ... MCP or shoulder joints ... Rheumatology #diagnosis #management
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
Idiopathic • Meniscal ... • Rheumatoid Arthritis ... Popliteal #BakersCyst #MSK ... #pathophysiology ... #signs #symptoms
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... burgdorferi (Lyme disease ... #Diagnosis #MSK