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management differential causes treatment guillain symptoms guillainbarre neuropathy parinauds peripheral sclerosis spinalcord acute algorithm als amyotrophic behcet blood central cerebritis
Guillain-Barre Syndrome An acute polyneuropathy (disorder Of the peripheral nervous System). Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
Criteria for Guillain Barre ... sensory symptoms or signs ... nervous system signs ... #Syndrome #diagnosis ... #criteria #neurology
Parinaud's Syndrome What? - Impaired upgaze - Light-near dissociation - Convergence retraction nystagmus - Eyelid retraction (Collier's
Parinaud's Syndrome ... → "setting sun sign ... " - Vascular disease ... #diagnosis #pineal ... #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease ... Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... #differential #diagnosis ... #neurology
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... #differential #diagnosis ... #causes #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Diagnosis: • ... #Syndrome #diagnosis ... management #treatment #neurology
Parinaud's syndrome What? • Light-near dissociation (tectal pupils) • Convergence retraction nystagmus • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... retraction (Collier's sign ... "setting sun" sign ... • Vascular disease ... #neurology #diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
mainly AQP4-lgG disease ... (AQP4-lgG disease ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
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