22 results
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Elevated levels ... days; its level elevated ... of developing AKI ... AKI at lower levels ... assessing the risk of AKI
RHABDOMYOLYSIS
•	Characterized by skeletal muscle breakdown & necrosis. 
•	Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. 
•	Defined based
Elevated Creatine ... • Half-life of CK ... is 1.5 days; elevated ... marker of muscle injury ... Rhabdomyolysis #trauma
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Kinase - Causes of Elevated ... - Seizures: Trauma ... infarction, Acute renal injury ... Creatine #Kinase #Elevated ... #CK #differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... and Differential ... Rhabdo-myolysis: CK ... syndrome: troponin, CK-MB ... Acute #Kidney #Injury
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm

 • Chronic Myocardial Injury: End
- Elevated Troponin ... Differential Diagnosis ... Toxins, Contusion/Trauma ... #Elevated #Troponin ... #Differential #
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... (AKI) in Patients ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Rhabdomyolysis - Differential ... Management Summary Trauma ... syndrome, Electrical injury ... Dermatomyositis) AKI ... Treatment: 1
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... (AKI) - Differential ... enlargement • Trauma ... Acute #Kidney #Injury ... #AKI #Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Rhabdomyolysis: • Trauma ... declines > ALT) • AKI ... + myoglobin AKI ... Rhabdomyolysis #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Hepatocellular Injury ... Demand ischemia • Trauma ... #differential #