10 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... Metformin + DPP4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Sulfonylureas GLP ... events TZDs DPP ... comparison #management #endocrinology ... #dm2
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
(Adlyxin) • DPP ... - Prevents GLP ... by inhibiting DPP ... #Management #pharmacology ... #DM2 #DMII #Classification
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... Increase Incretins (GLP-I ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... -4 inhibitor, GLP ... #Mellitus #DM2 ... #Medications #pharmacology ... comparison #table #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Receptor #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
) - First Oral GLP ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology # ... Endocrinology