1443 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
use in cellular metabolism ... via anaerobic metabolism ... also includes symptoms ... of metabolic acidosis ... LacticAcidosis #Toxicity #Toxicology
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Renal failure • Metabolic ... Colchicine #Toxicity #Toxicology ... #Symptoms #Signs
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... effect on negative symptoms ... following first-pass metabolism ... - Metabolism - ... #Clozapine #Toxicology
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... ingestion/exposure Symptoms ... Labs: Anion-Gap Metabolic ... Aspirin #Toxicity #Toxicology
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
post-ingestion) - Symptom ... deterioration Shock and metabolic ... - Anion gap metabolic ... Poisoning #Toxicity #Toxicology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
cause an anion gap metabolic ... Recovery from GI symptoms ... Ill Shock and metabolic ... acidosis • Metabolic ... Iron #Toxicity #Toxicology
Differential Considerations for a Seizure or Seizure-like Event
The following diagnoses may have presentations that can be
Mass lesions TOXICOLOGIC ... Extrapyramidal symptoms ... METABOLIC -
Toxicologic Assessment of Cyanosis (Goldfrank’s Toxicology)
#Diagnosis #Management #Toxicology #Cyanosis #Methemoglobinemia #Assessment #Algorithm
Toxicologic Assessment ... Cyanosis (Goldfrank’s Toxicology ... Diagnosis #Management #Toxicology
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Pathophysiology #Toxicology ... EthyleneGlycol #Metabolism
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
route of APAP metabolism ... formation of the toxic metabolite ... conjugate the toxic metabolite ... routes of liver metabolism ... #Pathophys #Toxicology