1001 results
High Dose Methotrexate - Toxicities and Pharmacology

Ashley & Brooke Barlow PharmD @theABofPharmaC

#High #Dose #Methotrexate #Pharmacology #oncology
High Dose Methotrexate ... Toxicities and Pharmacology ... #High #Dose #Methotrexate ... #Pharmacology #
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Azathioprine, Methotrexate ... Immunosuppressant #Drugs #Pharmacology
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
Demeclocycline) • Methotrexate ... Mnemonic #Drugs #pharmacology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
sulfamethoxazole, methotrexate ... Medications #Drugs #pharmacology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... Kat_Watson #Methotrexate ... Toxicity #Management #Pharmacology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... mercaptopurine, Weekly oral methotrexate ... pneumonia, IT methotrexate ... L-Asparaginase, IT methotrexate
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate 
 - Hemodynamically stable 
 - No
Pregnancy with Methotrexate ... examination #Methotrexate
Clinical Pharmacologic Properties of Antiarrhythmic Drugs

#Antiarrhythmic #Drugs #Medications #Pharmacology #Cardiology #Table #Effects
Clinical Pharmacologic ... #Medications #Pharmacology
Pharmacologic Treatment of Hyperthyroidism

#Hyperthyroidism #Treatment #Management #Pharmacology #Medications #Comparison #Table #Endocrinology #AAFP #Propylthiouracil #Methimazole
Pharmacologic Treatment ... Treatment #Management #Pharmacology
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Disease Activity - Methotrexate