1285 results
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Treatment Schema ... Intrathecal (IT) methotrexate ... protection: • IT methotrexate ... given throughout treatment ... Lymphoblastic #Leukemia #Treatment
Candidates for Medical Treatment of Ectopic Pregnancy with Methotrexate 
 - Hemodynamically stable 
 - No
Candidates for Medical Treatment ... Pregnancy with Methotrexate ... comply with post-treatment ... examination #Methotrexate
Rheumatoid Arthritis - ACR 2021 Guidelines
 - Low Disease Activity
 - Moderate to High Disease Activity
Disease Activity - Methotrexate ... Tapering DMARDs - Treatment ... Guidelines #management #treatment
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal ... • Start pre-treatment ... 48 hours post Treatment ... until levels of methotrexate ... @kdjhaveri #Methotrexate
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
Pneumonitis • Treatment ... Related: Radiation, Methotrexate
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Crystal nephropathy: Methotrexate
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease Treatment ... of steroids +/- methotrexate
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... IgG4+ cells" Treatment ... cyclophosphamide, methotrexate ... phenotypes #workup #treatment
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
Treatment of giant ... • Methotrexate : ... arteritis #GCA #Treatment
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
exam and imaging Treatment ... injections • DMARDs: Methotrexate