22 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
fragmentation hemolysis ... Scleroderma renal crisis ... • Mechanical hemolysis ... differential #diagnosis #hematology ... #hemolysis
Sickle Cell Vaso-Occlusive Crisis

#SickleCell #Crisis #Vasoocclusive #AcuteChestSyndrome #ACS #Pathophysiology #Hematology
Vaso-Occlusive Crisis ... #SickleCell #Crisis ... AcuteChestSyndrome #ACS #Pathophysiology ... #Hematology
Pathophysiology, Signs and Symptoms of Hemolytic Anemia

#Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... and Symptoms of Hemolytic ... Anemia #Pathophysiology ... #Hemolytic #Anemia ... #hematology #diagnosis
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... Wilsons #Disease #hemolytic ... #anemia #Hematology ... #pathophysiology
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology ... of Hemolytic Anemia ... environment #Pathophysiology ... #Hemolytic #Anemia ... #hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... AIHA #Autoimmune #Hemolytic ... #Anemia #Pathophysiology ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... (oroya fever), babesia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Bartonella, Babesia ... udaygulati #Hemolytic ... classification #hematology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... sickling.Vaso-occlusive crisis ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Biochemistry and Metabolism of Bilirubin
Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
of Bilirubin Hemolysis ... Biochemistry #Metabolism #pathophysiology ... #hepatology