17 results
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Diagnosis for Hemolytic ... Bartonella, Babesia ... udaygulati #Hemolytic ... Diagnosis #causes #classification ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
= (Retic %) x (Hct ... long (in days) it ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
to 280 U/L • It ... bloodstream Hemolysis ... : • Hemolytic ... deficiency of red blood ... The presence of macro-LDH
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... Immunoglobulin M (IgM) • Blood ... Mycoplasma, EBV, HIV ... sensitize red blood ... #anemia #hematology
Pulmonary Hypertension Groups - WHO Classification
Group I - Vascular remodeling of pulmonary arteries
 • Idiopathic, HIV,
Hypertension Groups - WHO Classification ... • Idiopathic, HIV ... causing back up of blood ... Sarcoidosis, chronic hemolytic ... PH Functional Classification
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... May have drop in Hct ... Extremely rare - HIV ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Hemolysis on labs ... May have drop in Hct ... Extremely rare - HIV ... diagnosis #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT ... ♀, ↑Age, ESRD Pathophysiology ... false ⊕’s, so use Bayesian ... likelihood of HIT ... Management #Treatment #Hematology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Red blood cell ... with mismatched blood ... types or during hemolytic ... Hypersensitivity #Types #Classification ... #Pathophysiology
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... a blockage in blood ... #Shock #Types #Pathophysiology ... criticalcare #diagnosis #classification