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diagnosis differential management anemia rheumatology classification hepatology algorithm causes treatment workup dermatology atlas clinical comparison reactions infectiousdiseases key liver microbiology
Hemolytic anemia in Wilson's disease #Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
Hemolytic anemia ... in Wilson's disease ... #Wilsons #Disease ... #hemolytic #anemia ... #Hematology #pathophysiology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell disease ... , Hemoglobin H disease ... (oroya fever), babesia ... Algorithm #workup #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... cells: Sickle cell disease ... #Peripheral #Blood ... Smear #Analysis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Causes: • Liver disease ... Bartonella, Babesia ... udaygulati #Hemolytic ... classification #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... , McLeod blood group ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... differential #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
= (Retic %) x (Hct ... Chronic kidney disease ... Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... and Associated Diseases ... Elliptocyte, Macro-ovalocyte ... Microscopy #Pathology #Hematology ... Pathologic Basis of Disease
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... Mycoplasma, EBV, HIV ... sensitize red blood ... #hemolytic #anemia ... #hematology #diagnosis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
to 280 U/L • It ... deficiency of red blood ... • Legionnaires disease ... The presence of macro-LDH ... or particular disease
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... spherocytosis, Hemolytic ... , Liver diseases ... Schistocytes - Hemolytic ... #differential #hematology
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